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US Grants Approval for Pig Kidney Transplant Trials

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A young genetically altered pig looking out from a warming box, in its pen at Revivicor Research farm, in Blacksburg, Virginia.PHOTO: AFP

Two US biotech companies say the Food and Drug Administration has cleared them to conduct clinical trials of their gene-edited pig kidneys for human transplants.

United Therapeutics along with another company, eGenesis, have been working since 2021 on experiments implanting pig kidneys into humans: initially brain-dead patients and more recently living recipients.

Advocates hope the approach will help address the severe organ shortage. More than 100,000 people in the United States are awaiting transplants, including over 90,000 in need of kidneys.

United Therapeutics’s approval, announced Monday, allows the company to advance its technology toward a licensed product if the trial succeeds.

The study authorization was hailed as a “significant step forward in our relentless mission to expand the availability of transplantable organs,” by Leigh Peterson, the company’s executive vice president.

The trial will initially enroll six patients with the end-stage renal disease before expanding to as many as 50, United Therapeutics said in a statement. The first transplant is expected in mid-2025.

Meanwhile, rival eGenesis said it had received FDA approval in December for a separate three-patient kidney study.

“The study will evaluate patients with kidney failure who are listed for a transplant but who face a low probability of receiving a deceased donor offer within a five-year timeframe,” the company said.

Xenotransplantation — transplanting organs from one species to another — has been a tantalizing yet elusive goal for science.

Early experiments in primates faltered, but advances in gene editing and immune system management have brought the field closer to reality.

Pigs have emerged as ideal donors: they grow quickly, produce large litters, and are already part of the human food supply.

United Therapeutics said trial patients would be monitored for life, assessing survival rates, kidney function, and the risk of zoonotic infections — diseases that jump from animals to humans.

Currently, there is only one living human recipient of a pig organ: Towana Looney, a 53-year-old from Alabama who received a United Therapeutics kidney on November 25, 2024.

She is also the longest-surviving recipient, having lived with a pig kidney for 71 days as of Tuesday. David Bennett of Maryland received a pig heart in 2022 and survived 60 days.

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Oyo confirms Lassa fever death in Ibadan, activates emergency response, traces contacts

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The Oyo State Government has confirmed a Lassa fever case at the University College Hospital, Ibadan, where a 44-year-old woman died, prompting the activation of emergency response measures and immediate contact tracing to contain the disease.

The state Commissioner for Health, Oluwaserimi Ajetunmobi, disclosed this in a statement on Wednesday, saying, “The patient died on April 11, 2026, while receiving treatment, while laboratory confirmation of Lassa fever was received on April 13.”

She added that the Ministry of Health had swiftly activated its emergency response system, including the establishment of an Incident Management System to coordinate response activities across the state.

According to her, “All identified contacts of the deceased are being closely monitored, while necessary measures have been taken to ensure a safe and dignified burial in line with public health protocols.”

Ajetunmobi urged residents to seek immediate medical attention if they experience symptoms such as persistent fever, weakness, sore throat, vomiting, diarrhoea, unexplained bleeding, chest pain or difficulty breathing.

She stressed, “Early presentation at health facilities significantly improves the chances of survival.”

The commissioner explained that Lassa fever is a viral haemorrhagic disease transmitted primarily through contact with food or household items contaminated by urine or faeces of infected rodents.

“It can also spread from person to person through contact with bodily fluids, especially in healthcare settings where infection prevention measures are not strictly observed,” she said.

She advised residents to maintain strict environmental hygiene, including proper waste disposal, safe storage of food in rodent-proof containers and avoiding drying food items on bare ground or roadsides.

Ajetunmobi also urged households to seal holes and entry points to prevent rodent access, while emphasising regular handwashing and good personal hygiene.

Residents, she said, should report suspected cases through designated emergency lines, while health workers must strictly adhere to infection prevention and control protocols.

Reaffirming the government’s commitment, the commissioner said surveillance had been intensified across the state, with all health facilities placed on alert.

“There is no cause for panic. The situation is under control, and Lassa fever is both preventable and treatable when detected early,” she assured.

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Rep Oseni Backs Ajimobi Widow’s Cancer Fight, Vows More Health Projects

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The lawmaker representing Ibarapa East/Ido Federal Constituency in the House of Representatives, Aderemi Oseni, has pledged to support the breast cancer awareness programme of the ABC Foundation founded by former Oyo First Lady, Dr. Florence Ajimobi.

Oseni, who is Chairman of the House Committee on Federal Roads Maintenance Agency (FERMA), made the commitment on Thursday in Ibadan at the flag-off of Pink Month 2025, an initiative of the foundation.

Contained in a statement by his media aide, Idowu Ayodele, the lawmaker described the campaign as a “lifesaving mission” given the rising burden of breast cancer in Nigeria, with over 28,000 new cases and thousands of deaths reported annually.

The APC chieftain said the free screening of 1,000 women planned by the foundation was timely, stressing that early detection remained the strongest weapon in the fight against cancer.

Hon. Aderemi Oseni exchanging pleasantries with former Oyo State First Lady, Dr. (Mrs.) Florence Ajimobi, at the event.

“Health is life. Only this June, I moved a motion at the National Assembly which led to the Federal Government subsidising dialysis treatment nationwide. Today, dialysis is either free or heavily discounted in federal health facilities,” Oseni said.

He listed his personal interventions to include funding hospital bills of indigent patients, construction of hospitals in Ido and Ibarapa East, establishment of primary health centres, and organisation of medical outreaches. He also disclosed plans to deploy mobile clinics to rural areas.

Commending Mrs. Ajimobi for sustaining her late husband’s legacy through humanitarian service, Oseni assured of partnership with the foundation, saying women’s wellbeing and empowerment remained central to his vision for Oyo State.

In her remarks, Mrs. Ajimobi said the foundation had offered medical care to over 85,000 patients and conducted more than 100,000 investigations since its inception. She added that the campaign was not just corporate social responsibility but “a moral duty and sacred trust.”

The former first lady, who lost her daughter Abisola to breast cancer earlier this year, said the experience had strengthened her resolve to save other families from such tragedy. She appealed to women to take advantage of the free screening and called on partners and development agencies to support the fight.

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Ayebae, Afolabi to headline D’Bio Wellness Summit

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Chairman of Fidson Healthcare Plc, Dr. Fidelis Akhagboso Ayebae, and Chief Executive Officer of Hazon Holdings, Dr. Victor ’Gbenga Afolabi, are set to lead discussions at the second edition of the D’Bio Wellness & Selfcare Summit.

The event is scheduled to hold on September 24 and 25 at the Lagos Chamber of Commerce and Industry (LCCI) Conference and Exhibition Centre, Alausa, Ikeja.

This year’s summit has the theme: “Self-Care as a Driver of Optimal Health and Wellness.”

Ayebae will serve as chairman of the event, while Afolabi, who is also the co-founder of Wellness HMO, will deliver the keynote address.

Ayebae, founder of Fidson Healthcare, is regarded as one of Nigeria’s leading pharmaceutical entrepreneurs. He is a fellow of the Institute of Directors Nigeria and the Institute of Corporate Affairs Management, and has held significant roles in the Manufacturers Association of Nigeria.

Afolabi has more than 20 years’ experience spanning healthcare, finance, technology and marketing. He is also the founder of the Eko Innovation Centre, a Lagos-based technology hub that supports start-ups and young entrepreneurs.

Convener of the summit, Dr. Monica Hemben Eimunjeze, said the event would focus on practical steps to improve health outcomes through self-care.

She said, “We are excited to welcome Dr. Ayebae and Dr. Afolabi as pivotal figures in our quest to enhance health literacy and empower individuals to prioritise self-care. This summit is not just about discussions; it is about actionable insights that can inspire and transform lives.”

The organisers said the two-day summit is open to the public and will feature panel sessions with health and wellness experts, attracting healthcare professionals, advocates and business leaders.

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