Health
WHO recommends dolutegravir as preferred HIV treatment option in all populations
Published
7 years agoon
By
Mega IconBased on new evidence assessing benefits and risks, the World Health Organization (WHO) recommends the use of the HIV drug dolutegravir (DTG) as the preferred first-line and second-line treatment for all populations, including pregnant women and those of childbearing potential.
Initial studies had highlighted a possible link between DTG and neural tube defects (birth defects of the brain and spinal cord that cause conditions such as spina bifida) in infants born to women using the drug at the time of conception. This potential safety concern was reported in May 2018 from a study in Botswana that found 4 cases of neural tube defects out of 426 women who became pregnant while taking DTG. Based on these preliminary findings, many countries advised pregnant women and women of childbearing potential to take efavirenz (EFV) instead.
New data from two large clinical trials comparing the efficacy and safety of DTG and EFV in Africa have now expanded the evidence base. The risks of neural tube defects are significantly lower than what the initial studies may have suggested.
The guidelines group also considered mathematical models of the benefits and harms associated with the two drugs; the values and preferences of people living with HIV, as well as factors related to implementation of HIV programmes in different countries, and cost.
DTG is a drug that is more effective, easier to take and has fewer side effects than alternative drugs that are currently used. DTG also has a high genetic barrier to developing drug resistance, which is important given the rising trend of resistance to EFV and nevirapine-based regimens. In 2019, 12 out of 18 countries surveyed by WHO reported pre-treatment drug resistance levels exceeding the recommended threshold of 10%.
All of above findings informed the decision to update the 2019 guidelines.
In 2019, 82 low- and middle-income countries reported to be transitioning to DTG-based HIV treatment regimens. The new updated recommendations aim to help more countries improve their HIV policies.
As for any medications, informed choice is important. Every treatment decision needs to be based on an informed discussion with the health provider weighing the benefits and potential risks.
WHO also stresses the importance of providing information and options to help women make an informed choice. To this end WHO has convened an advisory group of women living with HIV from diverse backgrounds to advise on policy issues related to their health, including sexual and reproductive health. WHO highlights the need to continually monitor the risk of neural tube defects associated with DTG.
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Health
Oyo confirms Lassa fever death in Ibadan, activates emergency response, traces contacts
Published
6 days agoon
April 16, 2026By
Mega IconThe Oyo State Government has confirmed a Lassa fever case at the University College Hospital, Ibadan, where a 44-year-old woman died, prompting the activation of emergency response measures and immediate contact tracing to contain the disease.
The state Commissioner for Health, Oluwaserimi Ajetunmobi, disclosed this in a statement on Wednesday, saying, “The patient died on April 11, 2026, while receiving treatment, while laboratory confirmation of Lassa fever was received on April 13.”
She added that the Ministry of Health had swiftly activated its emergency response system, including the establishment of an Incident Management System to coordinate response activities across the state.
According to her, “All identified contacts of the deceased are being closely monitored, while necessary measures have been taken to ensure a safe and dignified burial in line with public health protocols.”
Ajetunmobi urged residents to seek immediate medical attention if they experience symptoms such as persistent fever, weakness, sore throat, vomiting, diarrhoea, unexplained bleeding, chest pain or difficulty breathing.
She stressed, “Early presentation at health facilities significantly improves the chances of survival.”
The commissioner explained that Lassa fever is a viral haemorrhagic disease transmitted primarily through contact with food or household items contaminated by urine or faeces of infected rodents.
“It can also spread from person to person through contact with bodily fluids, especially in healthcare settings where infection prevention measures are not strictly observed,” she said.
She advised residents to maintain strict environmental hygiene, including proper waste disposal, safe storage of food in rodent-proof containers and avoiding drying food items on bare ground or roadsides.
Ajetunmobi also urged households to seal holes and entry points to prevent rodent access, while emphasising regular handwashing and good personal hygiene.
Residents, she said, should report suspected cases through designated emergency lines, while health workers must strictly adhere to infection prevention and control protocols.
Reaffirming the government’s commitment, the commissioner said surveillance had been intensified across the state, with all health facilities placed on alert.
“There is no cause for panic. The situation is under control, and Lassa fever is both preventable and treatable when detected early,” she assured.
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Health
Rep Oseni Backs Ajimobi Widow’s Cancer Fight, Vows More Health Projects
Published
7 months agoon
October 2, 2025By
Mega IconThe lawmaker representing Ibarapa East/Ido Federal Constituency in the House of Representatives, Aderemi Oseni, has pledged to support the breast cancer awareness programme of the ABC Foundation founded by former Oyo First Lady, Dr. Florence Ajimobi.
Oseni, who is Chairman of the House Committee on Federal Roads Maintenance Agency (FERMA), made the commitment on Thursday in Ibadan at the flag-off of Pink Month 2025, an initiative of the foundation.
Contained in a statement by his media aide, Idowu Ayodele, the lawmaker described the campaign as a “lifesaving mission” given the rising burden of breast cancer in Nigeria, with over 28,000 new cases and thousands of deaths reported annually.
The APC chieftain said the free screening of 1,000 women planned by the foundation was timely, stressing that early detection remained the strongest weapon in the fight against cancer.
Hon. Aderemi Oseni exchanging pleasantries with former Oyo State First Lady, Dr. (Mrs.) Florence Ajimobi, at the event.
“Health is life. Only this June, I moved a motion at the National Assembly which led to the Federal Government subsidising dialysis treatment nationwide. Today, dialysis is either free or heavily discounted in federal health facilities,” Oseni said.
He listed his personal interventions to include funding hospital bills of indigent patients, construction of hospitals in Ido and Ibarapa East, establishment of primary health centres, and organisation of medical outreaches. He also disclosed plans to deploy mobile clinics to rural areas.
Commending Mrs. Ajimobi for sustaining her late husband’s legacy through humanitarian service, Oseni assured of partnership with the foundation, saying women’s wellbeing and empowerment remained central to his vision for Oyo State.
In her remarks, Mrs. Ajimobi said the foundation had offered medical care to over 85,000 patients and conducted more than 100,000 investigations since its inception. She added that the campaign was not just corporate social responsibility but “a moral duty and sacred trust.”
The former first lady, who lost her daughter Abisola to breast cancer earlier this year, said the experience had strengthened her resolve to save other families from such tragedy. She appealed to women to take advantage of the free screening and called on partners and development agencies to support the fight.
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Health
Ayebae, Afolabi to headline D’Bio Wellness Summit
Published
7 months agoon
September 22, 2025By
Mega Icon
Chairman of Fidson Healthcare Plc, Dr. Fidelis Akhagboso Ayebae, and Chief Executive Officer of Hazon Holdings, Dr. Victor ’Gbenga Afolabi, are set to lead discussions at the second edition of the D’Bio Wellness & Selfcare Summit.
The event is scheduled to hold on September 24 and 25 at the Lagos Chamber of Commerce and Industry (LCCI) Conference and Exhibition Centre, Alausa, Ikeja.
This year’s summit has the theme: “Self-Care as a Driver of Optimal Health and Wellness.”
Ayebae will serve as chairman of the event, while Afolabi, who is also the co-founder of Wellness HMO, will deliver the keynote address.
Ayebae, founder of Fidson Healthcare, is regarded as one of Nigeria’s leading pharmaceutical entrepreneurs. He is a fellow of the Institute of Directors Nigeria and the Institute of Corporate Affairs Management, and has held significant roles in the Manufacturers Association of Nigeria.
Afolabi has more than 20 years’ experience spanning healthcare, finance, technology and marketing. He is also the founder of the Eko Innovation Centre, a Lagos-based technology hub that supports start-ups and young entrepreneurs.
Convener of the summit, Dr. Monica Hemben Eimunjeze, said the event would focus on practical steps to improve health outcomes through self-care.
She said, “We are excited to welcome Dr. Ayebae and Dr. Afolabi as pivotal figures in our quest to enhance health literacy and empower individuals to prioritise self-care. This summit is not just about discussions; it is about actionable insights that can inspire and transform lives.”
The organisers said the two-day summit is open to the public and will feature panel sessions with health and wellness experts, attracting healthcare professionals, advocates and business leaders.
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