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COVID-19: Seven have died in UK after receiving AstraZeneca vaccine, says regulator

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The UK medical regulator said Saturday that out of 30 people who suffered rare blood clots after receiving the Oxford-AstraZeneca vaccine, seven have died.

The British acknowledgement of deaths comes as several European countries have paused the use of the AstraZeneca jab over a potential link to blood clots.

The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) said in a statement that “Out of the 30 reports up to and including 24 March, sadly 7 have died.”

The reports of thrombosis, submitted by medics or members of the public via a government website, came after 18.1 million doses of the vaccine had been administered in the country.

Most of the cases (22) were a rare clotting condition called cerebral venous sinus thrombosis. Eight cases saw people suffer other types of thrombosis combined with low levels of blood platelets, which help blood clot.

There were no reports of blood clots from the Pfizer-BioNTech vaccine, the UK regulator said, adding that “our thorough review into these reports is ongoing”.

But MHRA chief executive Dr June Raine stressed that the benefits far outweighed any risks. “The public should continue to get their vaccine when invited to do so,” she said.

Europe update expected

Both the MHRA and European Medicines Agency (EMA) say no causal link has yet been established between the blood clotting case and the AstraZeneca vaccine.

But growing concerns have prompted a number of countries to pause rollout of the vaccine or limit it to older people due to the relatively young age of those who suffered blood clots.

Netherlands on Friday halted vaccinations with the AstraZeneca jab for people under the age of 60 after five new cases among younger women, one of whom died.

Germany has suspended the use of the vaccine for those under 60 after 31 cases of blood clots, most of them among younger and middle-aged women.

A number of other countries including France have imposed a similar age restrictions, while Denmark and Norway have suspended all use of the vaccine.

The European Medicines Agency (EMA), which like the World Health Organization previously declared the AstraZeneca vaccine safe, is expected to announce updated advice on the issue on April 7.

It said Wednesday that there had been 62 cases worldwide of cerebral venous sinus thrombosis, 44 of them in the European Economic Area, which includes the European Union, Iceland, Liechtenstein and Norway.

This figure did not include all Germany’s cases, however.

More than 9.2 million AstraZeneca jabs have been administered in the region.

The EMA said it believes the vaccine is safe and that experts have found no specific risk factors such as age, gender or medical history.

‘Weight of evidence’

Paul Hunter, a medical microbiologist at Britain’s University of East Anglia, told AFP that he had initially thought the link between vaccination and blood clots was likely to be a “random association”.

As evidence mounts of clusters in separate countries, “the weight of evidence is now looking towards Oxford-AstraZeneca actually being the cause of these adverse events”, he said.

Nevertheless, the risk for the unvaccinated of dying from Covid is “substantially greater,” he said.

A spokeswoman for AstraZeneca told AFP that patient safety is its “highest priority”.

UK, EU and World Health Organization regulatory bodies have concluded that the benefits “significantly outweigh the risks across all adult age groups”, she said.

AstraZeneca said last month following US efficiency trials that its vaccine is 76 percent effective at preventing the disease. It also said data for the EU and the UK showed no increased risk of blood clots.

The UK has administered more than 31 million first vaccine doses, using both the Oxford-AstraZeneca and the Pfizer-BioNTech jabs. People cannot choose which one they get.

The UK in June 2020 ordered 100 million doses of the Oxford-AstraZeneca vaccine and supported its development. It also ordered 30 million doses of the Pfizer-BioNTech vaccine the same year.

 

AFP

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Oyo: Tragedy As Bride-to-Be Among Four Dead in Suspected Lassa Fever Outbreak

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The Oyo State Ministry of Health has closed two hospitals in Saki West Local Government Area following a suspected outbreak of Lassa fever, which has claimed four lives.

The fatalities, confirmed by the Oyo State Rapid Response Team (RRT), include three males and a 32-year-old female who was preparing for her wedding. The closure of the hospitals aims to contain the spread of the disease and ensure thorough decontamination.

In a press statement issued by the Commissioner for Information and Orientation, Dotun Oyelade, the State Commissioner for Health, Dr. Oluwaserimi Ajetunmobi, revealed that the RRT was dispatched to Saki following distress calls from residents reporting mysterious deaths.

Findings and Immediate Actions

The RRT, comprising health officials, representatives from WHO and the Red Cross, and local health authorities, conducted a comprehensive investigation into the outbreak.

Preliminary findings suggest that an apprentice at one of the affected hospitals, who had recently returned from Iwajowa Local Government Area, might have introduced the infection.

The team disclosed that the deceased exhibited symptoms consistent with Lassa fever, such as craniofacial bleeding. The hospital owner, who was among the deceased, initially self-medicated with antimalarials and antibiotics before seeking hospital care when his condition worsened.

Containment Measures

Both the hospital where the fatalities occurred and the facility that admitted the hospital owner were shut down for decontamination.

Contact tracing efforts are ongoing, focusing on high-risk individuals who had contact with the deceased during their illness or burial.

Affected health workers were trained on Infection Prevention and Control (IPC) protocols, and public awareness campaigns were conducted to educate residents about Lassa fever.

Samples have been collected from a symptomatic individual, pending laboratory confirmation. Line-listing of contacts is underway to identify potential cases and prevent further spread.

Collaborative Efforts

The RRT also paid an advocacy visit to the Okere of Saki’s palace to brief traditional authorities on the situation. Local government officials in Saki West were engaged to coordinate containment strategies.

Reports indicate that while the outbreak initially affected Saki West, it has extended to Iwajowa and Kajola Local Government Areas.

Disease Surveillance and Notification Officers (DSNOs) in the affected LGAs have been instructed to commence preliminary containment measures as the State RRT ramps up its response.

Call for Vigilance

The Ministry of Health has urged residents to remain vigilant, report any symptoms suggestive of Lassa fever, and adhere to preventive measures.

These include proper hygiene practices, avoiding contact with rodents, and seeking medical attention promptly if symptoms arise.

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Oyo: Oseni to Launch Mobile Clinic Initiative to Revitalize Rural Healthcare

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A member representing Ibarapa East/Ido federal constituency of Oyo State at the House of Representatives, Engr. Aderemi Oseni, has announced a plan to launch a “Mobile Clinic” programme aimed at providing essential healthcare services directly to rural communities across the constituency.

Scheduled to begin in the first quarter of 2025, this initiative underscores Oseni’s commitment to expanding healthcare access, particularly for underserved populations.

Speaking on Saturday at the 10th-anniversary celebration of God’s Knot Hospital in Ologuneru, Ibadan, the lawmaker, who also chairs the House Committee on the Federal Roads Maintenance Agency (FERMA), highlighted the programme’s primary objective: bringing healthcare closer to the people.

“Every community deserves attention; healthcare should never be bound by geographical barriers,” Oseni stated.

He explained that the mobile clinics would deliver essential health check-ups, screenings, and preventive care in remote areas, allowing residents to access quality healthcare without traveling long distances.

As part of his broader healthcare agenda, Oseni informed, through a statement by his media aide, Idowu Ayodele, that he has already facilitated the construction of two fully equipped maternity centers within his constituency, both slated for commissioning before December 2024. He also disclosed plans to establish two modern general hospitals in 2025, further strengthening his commitment to building a healthier community.

The lawmaker expressed interest in collaborating with God’s Knot Hospital on the mobile clinic project, calling for partnerships to support sustainable healthcare initiatives that enhance the quality of life for vulnerable populations in the constituency.

“I resonate deeply with the mission of God’s Knot Hospital,” Oseni shared, adding that such partnerships would significantly improve healthcare in Oyo State”.

The anniversary event attracted distinguished guests, including former Ondo State Governor Dr. Olusegun Mimiko, whom Oseni commended for his contributions to healthcare, particularly through the Mother and Child Hospitals that transformed maternal and child healthcare in Ondo State.

Oseni urged philanthropists, government bodies, and international organizations to support healthcare projects like the upcoming mobile clinics, emphasising that the improvement of healthcare services is a shared responsibility.

 

 

 

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NAFDAC Shuts Maiduguri Market Over Sun-Dried Drugs After Flood

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The National Agency for Food and Drug Administration and Control (NAFDAC) has ordered the immediate closure of the Gomboru drug market in Maiduguri following severe flooding that submerged the area and contaminated the drugs sold within the market.

In a statement posted on its official X handle, NAFDAC disclosed that the decision was made after reports surfaced that contaminated drugs, which had been washed and sun-dried for resale, were being sold at the market.

“After the recent flooding in Maiduguri that submerged the Gomboru drug market where contaminated drugs were washed and sun-dried for resale, the @DGatNAFDAC ordered the immediate closure of the market to conduct a thorough shop-to-shop removal of these compromised drugs,” the agency wrote.

The flooding, which ravaged Maiduguri, was triggered by the rupture of the Alau dam on the Ngadda River, located 20 kilometers (12 miles) south of the city.

The floodwaters claimed at least 30 lives and displaced 400,000 residents, leaving large parts of the city and surrounding areas in devastation.

NAFDAC’s intervention is aimed at safeguarding public health by preventing the sale and consumption of contaminated drugs.

The agency has mobilized teams to inspect the market and ensure the removal of all compromised pharmaceutical products.

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