Health
Africa: As COVID-19 devastates health systems, over 6,000 additional children could die a day – UNICEF
An additional 6,000 children under five could die every day from preventable causes over the next six months as the COVID-19 pandemic continues to weaken health systems and disrupt routine services, UNICEF said today.
The estimate is based on an analysis by researchers from the Johns Hopkins Bloomberg School of Public Health, newly published in The Lancet Global Health journal. Based on the worst of three scenarios in 118 low- and middle-income countries, the analysis estimates that an additional 1.2 million under-five deaths could occur in just six months, due to reductions in routine health service coverage levels and an increase in child wasting.
These potential child deaths will be in addition to the 2.5 million children who already die before their 5th birthday every six months in the 118 countries included in the study, threatening to reverse nearly a decade of progress on ending preventable under-five mortality.
Some 56,700 more maternal deaths could also occur in just six months, in addition to the 144,000 deaths that already take place in the same countries over a six-month period.
“Under a worst-case scenario, the global number of children dying before their fifth birthdays could increase for the first time in decades,” said UNICEF Executive Director Henrietta Fore. “We must not let mothers and children become collateral damage in the fight against the virus. And we must not let decades of progress on reducing preventable child and maternal deaths be lost.”
In countries with already weak health systems, COVID-19 is causing disruptions in medical supply chains and straining financial and human resources. Visits to health care centres are declining due to lockdowns, curfews and transport disruptions, and as communities remain fearful of infection. In a commentary to the Lancet report, UNICEF warns these disruptions could result in potentially devastating increases in maternal and child deaths.
The paper analyzes three scenarios for the impact of reductions in lifesaving interventions due to the crisis on child and maternal deaths. It warns that in the least severe scenario, where coverage is reduced around 15 per cent, there would be a 9.8 per cent increase in under-five child deaths, or an estimated 1,400 a day, and an 8.3 per cent increase in maternal deaths. In the worst-case scenario, where health interventions are reduced by around 45 per cent, there could be as much as a 44.7 per cent increase in under-five child deaths and 38.6 per cent increase in maternal deaths per month.
These interventions range from family planning, antenatal and postnatal care, child delivery, vaccinations and preventive and curative services. The estimates show that if, for whatever reason, routine health care is disrupted and access to food is decreased, the increase in child and maternal deaths will be devastating. The greatest number of additional child deaths will be due to an increase in wasting prevalence among children, which includes the potential impact beyond the health system, and reduction in treatment of neonatal sepsis and pneumonia.
According to the modeling, and assuming reductions in coverage in the worst-case scenario, the 10 countries that could potentially have the largest number of additional child deaths are: Bangladesh, Brazil, Democratic Republic of the Congo, Ethiopia, India, Indonesia, Nigeria, Pakistan, Uganda and United Republic of Tanzania.
The 10 countries that are most likely to witness the highest excess child mortality rates under the worst-case scenario are: Djibouti, Eswatini, Lesotho, Liberia, Mali, Malawi, Nigeria, Pakistan, Sierra Leone and Somalia. Continued provision of life-saving services is critical in these countries.
In addition to the estimated potential rise in under-five and maternal deaths described in the Lancet Global Health Journal analysis, UNICEF is deeply alarmed by the other knock-on effects of the pandemic on children:
- An estimated 77 per cent of children under the age of 18 worldwide – 1.80 billion out of 2.35 billion – were living in one of the 132 countries with stay-at-home policies, as of early May.
- Nearly 1.3 billion students – over 72 per cent – are out of school as a result of nationwide school closures in 177 countries.
- 40 per cent of the world’s population are not able to wash their hands with soap and water at home.
- Nearly 370 million children across 143 countries who normally rely on school meals for a reliable source of daily nutrition must now look to other sources as schools are shuttered.
- As of 14 April, over 117 million children in 37 countries may miss out on their measles vaccination as the pandemic causes immunization campaigns to stop to reduce the risk of spreading the virus.
This week, UNICEF is launching #Reimagine, a global campaign to prevent the COVID-19 pandemic from becoming a lasting crisis for children, especially the most vulnerable children – such as those affected by poverty, exclusion or family violence. Through the campaign, UNICEF is issuing an urgent appeal to governments, the public, donors and the private sector to join UNICEF as we seek to respond, recover and reimagine a world currently besieged by the coronavirus:
- Respond. We must act now to stop the disease from spreading, help the sick, and protect first responders on the frontlines risking their own lives to save others.
- Recover. Even when the pandemic slows, each country will have to continue to work to mitigate the knock-on effects on children and address the damage inflicted. Communities will also have to work together, and across borders to rebuild and prevent a return of the disease.
- Reimagine. If we have learned anything from COVID-19, it’s that our systems and policies must protect people, all the time, not just in the event of a crisis. As the world recovers from the pandemic, now is the time to lay the groundwork for building back better.
To kickstart the campaign, two of UNICEF’s valued partners – Pandora and ING – have both agreed to pledge a generous donation to show their part in answering the call to this appeal and to spur more donations from the public in the coming weeks.
“The COVID-19 crisis is a child rights crisis. We need an immediate-, medium- and long-term response that not only addresses the challenges created by the pandemic and its secondary impacts on children, but also outlines a clear version for building back a better world when the crisis finally recedes. For that, we need everyone’s ideas, resources, creativity and heart.” said Fore. “It is our shared responsibility today, to reimagine what the world will look like tomorrow.”
The West African Society of Parenteral & Enteral Nutrition (WASPEN) has called on President Bola Ahmed Tinubu to make clinical malnutrition a national healthcare priority, warning that the crisis is growing but remains largely overlooked in Nigeria’s healthcare system.
WASPEN’s Founder and President, Dr. Teresa Pounds, made this appeal on Monday during a press conference ahead of the 2025 WASPEN Clinical Nutrition Conference, scheduled for June 17–19 in collaboration with the National Hospital Abuja.
Themed “Bridging the Gap: Integrating Hospital and Community Malnutrition Care in Developing Countries,” the event aims to foster solutions for hospital and community malnutrition.
Describing malnutrition as “the skeleton in the hospital’s closet,” Dr. Pounds emphasised the need for urgent awareness, policy reform, and collaboration among healthcare stakeholders to ensure effective hospital nutrition programs.
“Many patients in Nigerian hospitals suffer from inadequate nutritional support, leading to prolonged hospital stays, increased complications, and higher mortality rates. This issue must be addressed at the highest level,” she stated.
The press conference was attended by the management of Genrith Pharmaceuticals Limited, a major partner, led by its CEO, Chief Emmanuel Umenwa.
Call for National Clinical Nutrition Policy
Dr. Pounds, a U.S.-based specialist in critical care nutrition and a board-certified nutrition support pharmacist, urged the government to implement a national policy framework to support specialised clinical nutrition interventions. She stressed the importance of integrating mandatory nutrition screening and intervention into all healthcare facilities.
She also called on the Federal and State Ministries of Health to expand and enforce standardised clinical nutrition policies, ensure hospitals conduct structured nutrition screening for all patients, makes medical nutrition therapy accessible and affordable, and support research and local production of specialised nutritional products.
She further encouraged NAFDAC, NIPRD, pharmaceutical companies, and NGOs to collaborate on research, funding, and product development to improve hospital and community-based nutritional care.
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“We need a national framework that ensures no patient suffers due to a lack of proper nutrition,” the expert stressed.
Conference to Attract Top Medical and Policy Experts
Speaking on the upcoming conference, Dr. Pounds noted that it will bring together leading medical experts, policymakers, and healthcare stakeholders to develop strategies for addressing malnutrition.
Prominent figures expected at the event include Prof. Ali Pate, Coordinating Minister of Health (Special Guest of Honour), Nyesom Wike, Minister of the FCT (Chief Host), Prof. Muhammad Raji Mahmud, Chief Medical Director, National Hospital Abuja (Host), Prof. Audu Bala, President, Nigerian Medical Association (Keynote Speaker), Pharm. Ibrahim Tanko Ayuba, President, Pharmaceutical Society of Nigeria (Guest of Honour), and Prof. Salisu Maiwada Abubaka, President, Nutrition Society of Nigeria (Guest of Honour) admiration.
Pre-Conference Activities
Prof. Raji Mahmud, Chief Medical Director of the National Hospital Abuja, represented by the Chairperson of the Local Organising Committee (LOC), Pharm. Adesola Clara assured that the hospital has the necessary facilities and expertise to host a successful conference. He emphasised that the hospital is fully prepared for the programme.
Also, the WASPEN Central Planning Committee, led by Mrs. Ghinsel Blessing, revealed that pre-conference activities will include a hands-on training workshop on nutritional kits in hospitals, scheduled for June 16, a health walk to raise awareness about hospital malnutrition, expected to be led by First Lady Sen. Oluremi Tinubu.
With malnutrition posing a silent but deadly threat to healthcare outcomes, WASPEN hopes that the Tinubu administration will take decisive action to integrate nutrition-focused interventions into Nigeria’s health policies.
The 2025 WASPEN Clinical Nutrition Conference is expected to be a game-changer in shaping the future of clinical nutrition in Nigeria and West Africa.
Two US biotech companies say the Food and Drug Administration has cleared them to conduct clinical trials of their gene-edited pig kidneys for human transplants.
United Therapeutics along with another company, eGenesis, have been working since 2021 on experiments implanting pig kidneys into humans: initially brain-dead patients and more recently living recipients.
Advocates hope the approach will help address the severe organ shortage. More than 100,000 people in the United States are awaiting transplants, including over 90,000 in need of kidneys.
United Therapeutics’s approval, announced Monday, allows the company to advance its technology toward a licensed product if the trial succeeds.
The study authorization was hailed as a “significant step forward in our relentless mission to expand the availability of transplantable organs,” by Leigh Peterson, the company’s executive vice president.
The trial will initially enroll six patients with the end-stage renal disease before expanding to as many as 50, United Therapeutics said in a statement. The first transplant is expected in mid-2025.
Meanwhile, rival eGenesis said it had received FDA approval in December for a separate three-patient kidney study.
“The study will evaluate patients with kidney failure who are listed for a transplant but who face a low probability of receiving a deceased donor offer within a five-year timeframe,” the company said.
Xenotransplantation — transplanting organs from one species to another — has been a tantalizing yet elusive goal for science.
Early experiments in primates faltered, but advances in gene editing and immune system management have brought the field closer to reality.
Pigs have emerged as ideal donors: they grow quickly, produce large litters, and are already part of the human food supply.
United Therapeutics said trial patients would be monitored for life, assessing survival rates, kidney function, and the risk of zoonotic infections — diseases that jump from animals to humans.
Currently, there is only one living human recipient of a pig organ: Towana Looney, a 53-year-old from Alabama who received a United Therapeutics kidney on November 25, 2024.
She is also the longest-surviving recipient, having lived with a pig kidney for 71 days as of Tuesday. David Bennett of Maryland received a pig heart in 2022 and survived 60 days.
The Swiss government said Thursday it aimed to overhaul its law on medically-assisted reproduction to legalise egg donations and give broader access to sperm donations.
Currently egg donations are not allowed and only married couples can access sperm donations.
The Swiss parliament has long said it wants to change that, and has asked the government with coming up with a proposal to provide broader access.
A government statement said it had “decided to completely revise the law on medically assisted reproduction in order to adapt it to the current context” and had asked the interior ministry to draft a proposed law by the end of next year.
The government said it wants to legalise egg donations in cases where a woman in a couple is infertile, as a parallel to the already legal use of sperm donations in cases of male sterility.
Bern said its priority was “the protection of donors and the welfare of the child”, stressing that “this protection cannot be guaranteed if parents resort to egg donation abroad”.
The government also said it wanted to expand access to both egg and sperm donation to unmarried couples.
After Switzerland legalised same-sex marriage in 2022, married lesbian couples have also had access to sperm donations.
But the government said the current law barring unmarried couples from access to such medically assisted reproduction was “outdated and no longer corresponds to social reality”.
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