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WHO calls for equitable access to future COVID-19 vaccines in Africa

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The World Health Organization (WHO) in Africa joined immunization experts in urging the international community and countries in Africa to take concrete actions to ensure equitable access to COVID-19 vaccines, as researchers around the world race to find effective protection against the virus.“It is clear that as the international community comes together to develop safe and effective vaccines and therapeutics for COVID-19, equity must be a central focus of these efforts,” said Dr Matshidiso Moeti, WHO Regional Director for Africa. “Too often, African countries end up at the back of the queue for new technologies, including vaccines. These life-saving products must be available to everyone, not only those who can afford to pay.”

WHO and partners launched the Access to COVID-19 Tools (ACT) Accelerator to speed up the development, production and equitable access to COVID-19 diagnostics, therapeutics and vaccines. It brings together leaders of government, global health organizations civil society groups, businesses and philanthropies to form a plan for an equitable response to the COVID-19 pandemic. WHO is collaborating with Gavi, the Vaccine Alliance and the Coalition for Epidemic Preparedness Innovations (CEPI) to ensure a fair allocation of vaccines to all countries, aiming to deliver 2 billion doses globally for high-risk populations, including 1 billion for low and middle-income countries.

The African Union has endorsed the need for Africa to develop a framework to actively engage in the development and access to COVID-19 vaccines. Countries can take steps now that will strengthen health systems, improve immunization delivery, and pave the way for the introduction of a COVID-19 vaccine. These include: mobilizing financial resources; strengthening local vaccine manufacturing, and regulatory, supply and distribution systems; building workforce skills and knowledge; enhancing outreach services; and listening to community concerns to counter misinformation.

Globally, there are nearly 150 COVID-19 vaccine candidates and currently 19 are in clinical trials. South Africa is the first country on the continent to start a clinical trial with the University of Witwatersrand in Johannesburg testing a vaccine developed by the Oxford Jenner Institute in the United Kingdom. The South African Ox1Cov-19 Vaccine VIDA-Trial is expected to involve 2000 volunteers aged 18–65 years and include some people living with HIV. The vaccine is already undergoing trials in the United Kingdom and Brazil with thousands of participants.

According to the African Academy of Sciences only 2% of clinical trials conducted worldwide occur in Africa. It is important to test the COVID-19 vaccine in countries where it is needed to ensure that it will be effective. With more than 215 000 cases, South Africa accounts for 43% of the continent’s total cases. Clinical trials must be performed according to international and national scientific and ethical standards, which include informed consent for any participant.

“I encourage more countries in the region to join these trials so that the contexts and immune response of populations in Africa are factored in to studies,” said Dr Moeti. “Africa has the scientific expertise to contribute widely to the search for an effective COVID-19 vaccine. Indeed, our researchers have helped develop vaccines which provide protection against communicable diseases such as meningitis, Ebola, yellow fever and a number of other common health threats in the region.”

Earlier, this month WHO Africa’s principle advisory group on immunization policies and programmes – the African Regional Immunization Technical Advisory Group (RITAG) – also noted the need to ensure equitable access to COVID-19 and other vaccines in the region.

“As the world focuses on finding a vaccine for COVID-19, we must ensure people do not forget that dozens of lifesaving vaccines already exist. These vaccines should reach children everywhere in Africa – no one can be left behind,” said Professor Helen Rees, Chair of the RITAG.

Initial analysis of the impact of the COVID-19 pandemic on immunization in the African Region suggests that millions of African children are likely to be negatively impacted, as routine immunization services and vaccination campaigns for polio, cholera, measles, yellow fever, meningitis and human papilloma virus have been disrupted.

Despite these challenges, RITAG members also noted significant milestones and markers of progress. For example, there have been tremendous gains in the fight against wild poliovirus, and the African Region is expected to be officially certified free of wild poliovirus in August 2020. The Democratic Republic of the Congo also announced the end of its 10th Ebola outbreak in eastern DRC, which was the worst in its history. An effective vaccine was a key tool in the response.

Dr Moeti spoke about COVID-19 vaccine development in Africa during a virtual press conference today organized by APO Group. She was joined by Professor Shabir Madhi, University of Witwatersrand, Principal Investigator of Oxford Covid-19 Vaccine Trial in South Africa; and Professor Pontiano Kaleebu, Director of the MCR/UVRI and LSHTM Ugandan Research Unit. The briefing was streamed on more than 300 African news sites as well as the WHO Regional Office for Africa’s Twitter and Facebook accounts.

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NAFDAC Shuts Maiduguri Market Over Sun-Dried Drugs After Flood

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The National Agency for Food and Drug Administration and Control (NAFDAC) has ordered the immediate closure of the Gomboru drug market in Maiduguri following severe flooding that submerged the area and contaminated the drugs sold within the market.

In a statement posted on its official X handle, NAFDAC disclosed that the decision was made after reports surfaced that contaminated drugs, which had been washed and sun-dried for resale, were being sold at the market.

“After the recent flooding in Maiduguri that submerged the Gomboru drug market where contaminated drugs were washed and sun-dried for resale, the @DGatNAFDAC ordered the immediate closure of the market to conduct a thorough shop-to-shop removal of these compromised drugs,” the agency wrote.

The flooding, which ravaged Maiduguri, was triggered by the rupture of the Alau dam on the Ngadda River, located 20 kilometers (12 miles) south of the city.

The floodwaters claimed at least 30 lives and displaced 400,000 residents, leaving large parts of the city and surrounding areas in devastation.

NAFDAC’s intervention is aimed at safeguarding public health by preventing the sale and consumption of contaminated drugs.

The agency has mobilized teams to inspect the market and ensure the removal of all compromised pharmaceutical products.

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Cholera Outbreak: Rep Oseni Urges Residents to Prioritise Hygiene, Safety Measures

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Engr. Aderemi Oseni, Chairman of the House Committee on Federal Road Maintenance Agency (FERMA) and the lawmaker representing Ibarapa East/Ido Federal Constituency of Oyo State has expressed deep concern following the recent outbreak of cholera cases in the state.

Cholera, a highly contagious bacterial infection transmitted through contaminated water and food, poses significant health risks, particularly in densely populated areas with inadequate sanitation.

Oseni urged residents of Oyo State, especially those in his constituency, to prioritise hygiene practices and strictly adhere to recommended safety measures, emphasising the critical importance of proactive measures to halt the disease’s spread.

In a statement issued on Monday by his media aide, Idowu Ayodele, in Ibadan, the state capital, the lawmaker underscored the necessity of maintaining clean water sources and practicing proper sanitation methods.

“Cholera outbreaks can be significantly reduced if we all take responsibility for our hygiene habits and ensure our surroundings are clean,” he stated.

The APC chieftain also stressed the urgency of seeking prompt medical attention at the first signs of symptoms such as diarrhea and vomiting, which are characteristic of cholera.

“Early detection and treatment are crucial in combating cholera and preventing its spread. Access to safe drinking water and adequate sanitation are fundamental rights that must be upheld, especially during health crises like this,” he asserted.

Oseni further called for unity and collective action in combating the cholera outbreak.

He expressed confidence that through concerted efforts and vigilant adherence to preventive measures, communities can contain and ultimately overcome this challenging public health issue.

“By working together, maintaining vigilance, and prioritising hygiene practices, we can effectively mitigate the impact of cholera on our communities,” the lawmaker concluded.

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Ondo Resident Doctors Begin 14-Day Warning Strike

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Resident doctors at the University of Medical Sciences Teaching Hospital (UNIMEDTH) in Ondo State have initiated a 14-day warning strike, as confirmed by the National Association of Resident Doctors (NARD).

The strike action, led by the association’s President, John Matthew, highlights various grievances, notably the non-payment of seven months’ salaries to new members.

Matthew added that the strike also addresses the non-payment of palliative to House Officers since February, the failure to disburse the February Hazard Allowance despite prior assurances from the state government, and the ongoing shortage of staff due to resignations.

Matthew lamented the drastic decrease in resident doctors, citing a decrease from 150 doctors to a mere 26 in recent months.

In response to the situation, he urged management to prioritise the full payment of arrears owed to members, immediate payment of the February 2024 palliative to house officers, and prompt disbursement of the February hazard allowance.

The association further called for urgent measures to address the critical shortage of clinical manpower within the institution.

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